Table 2.
Clinical presentation and measurements of 20 cases followed for more than 3 months.
| Case | Sex | Age at diagnosis (years) | Initial measurements of the tumor (mm) | Final measurements of the tumor (mm) | Follow-up period (months) | Number of measurements | TV-DR (/year) | hTV-DR (/year) | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D1 | D2 | D3 | D1 | D2 | D3 | |||||||
| 1 | F | 19 | 32 | 25 | 24 | 33 | 22 | 19 | 4 | 2 | −1.21 | 1.71 |
| 2 | M | 19 | 26 | 16 | 16 | 25 | 16 | 13 | 3 | 2 | −1.20 | 1.69 |
| 3 | F | 19 | 9 | 6 | 9 | 8 | 6 | 7 | 7 | 2 | −0.91 | 1.48 |
| 4 | M | 16 | 24 | 20 | 17 | 26 | 17 | 16 | 3 | 2 | −0.80 | 1.99 |
| 5 | F | 19 | 21 | 15 | 13 | 20 | 15 | 9 | 40 | 6 | −0.17 | 1.64 |
| 6 | F | 15 | 16 | 12 | 10 | 15 | 14 | 12 | 6 | 4 | −0.13 | 2.01 |
| 7 | F | 18 | 7 | 6 | 6 | 6 | 6 | 5 | 30 | 6 | −0.08 | 1.53 |
| 8 | F | 18 | 12 | 9 | 8 | 14 | 8 | 8 | 4 | 3 | 0.09 | 1.64 |
| 9 | F | 18 | 10 | 9 | 7 | 12 | 10 | 10 | 51 | 10 | 0.25 | 1.59 |
| 10 | F | 15 | 18 | 17 | 14 | 20 | 18 | 13 | 5 | 2 | 0.28 | 2.07 |
| 11 | F | 18 | 9 | 8 | 6 | 15 | 10 | 8 | 60 | 7 | 0.30 | 1.53 |
| 12 | F | 17 | 27 | 20 | 17 | 29 | 20 | 17 | 3 | 2 | 0.39 | 1.86 |
| 13 | F | 19 | 16 | 10 | 11 | 17 | 10 | 12 | 5 | 2 | 0.50 | 1.61 |
| 14 | F | 15 | 10 | 7 | 6 | 13 | 7 | 6 | 5 | 2 | 0.90 | 1.84 |
| 15 | F | 16 | 7 | 5 | 7 | 7 | 6 | 7 | 3 | 2 | 0.91 | 1.70 |
| 16 | F | 16 | 31 | 17 | 16 | 29 | 19 | 18 | 3 | 2 | 0.92 | 1.94 |
| 17 | M | 19 | 44 | 38 | 28 | 43 | 42 | 34 | 3 | 2 | 1.21 | 1.81 |
| 18 | F | 12 | 29 | 24 | 15 | 35 | 24 | 16 | 3 | 2 | 1.36 | 2.66 |
| 19 | F | 18 | 17 | 12 | 10 | 19 | 14 | 12 | 4 | 2 | 1.73 | 1.70 |
| 20 | F | 13 | 8 | 4 | 4 | 15 | 12 | 7 | 19 | 4 | 1.89 | 1.96 |
D1: maximum tumor diameter, D2: diameter perpendicular to the maximum tumor diameter, and D3: depth (mm). TV-DR: tumor volume-doubling rate; hTV-DR: hypothetical tumor volume-doubling rate before presentation. Cases 7, 9, and 11 were under active surveillance at the end of the study period. Cases 5 and 20 underwent thyroidectomy after 19 and 40 months of follow-up, respectively.