Scheme 1.

Dual repair and biosynthetic function of P. cubensis PsiK (red). The enzyme catalyzes 4‐hydroxtryptamine phosphorylation to norbaeocystin during 1 biosynthesis or repairs 1 by re‐phosphorylation of 2. In the mushrooms, the methyltransferase PsiM (grey) completes 1 biosynthesis after the phosphorylation step.