Illustration of Step 1: the collaborative question and answer exercise
Question derived from Review 2 (qualitative evidence) posed to Review 1 (quantitative evidence)	Response from Review 1 (quantitative evidence)
Is there any evidence for interventions tailored to the specific needs of the child being more effective than ones which are not?	Some evidence that programmes tailored to the LTC might be more effective than those which are not, eg, tailored to children of a certain age.
Question derived from Review 1 (quantitative evidence) posed to Review 2 (qualitative evidence)	Response from Review 2 (qualitative evidence)
Interventions in Review 1 were delivered either in a hospital/clinic, school, or at home/over the telephone. Does Review 2 suggest that the setting is a factor that affects the effectiveness of an intervention?	Yes, broadly the setting needs to be accessible and aspects of the setting may affect the extent to which an intervention is perceived to be engaging (see theme 1). Theme 2 regarding safe space implies that as well as the intervention staff, it is important that the setting is familiar and allows for a therapeutic atmosphere. A setting that allows for privacy and anonymity is seen as a positive thing in some studies and as such there are benefits of online interventions. The majority of Review 2 interventions were delivered in hospital/clinics (17 studies), very few were delivered at home, school or by phone. Online setting was next most frequent in 13 studies

Illustration of step 3: Description of categories and contribution of findings from each review
Category	Summary	Contribution from Review 1	Contribution from Review 2	Implications
Accessibility and delivery of interventions	Considers the role of the setting, use of technology and flexibility of an intervention in ensuring that it can be accessed by children and young people with a long‐term condition	Some evidence that accessibility and familiarity if interventions may be beneficial, but difficult to tease out from other components of interventions	Familiar setting, use of technology and “therapists” who can relate to the needs of young people all perceived to be effective	Further research to investigate the impact of accessibility and delivery on the effectiveness of interventions is warranted