Table 3.
Yield of the second round relative to FIT results of the first round
| First screening round FIT result (Hb/g feces) | 0 μg | >0 and <15 μg | ≥15 and <47 μg | p‐value |
|---|---|---|---|---|
| Total | 248,310 | 66,030 | 10,961 | |
| Positivity rate | ||||
| n (%) | 6,000 (2.4) | 5,187 (7.9) | 2,553 (23.3) | <0.001 |
| Odds‐ratio (95% CI) | – | 3.4 (3.3–3.5)1 | 11.9 (11.3–12.5)1 | |
| PPV AN | ||||
| n (%) | 1,390 (27.9) | 1,993 (45.7) | 1,319 (60.3) | <0.001 |
| Odds‐ratio (95% CI) | – | 2.2 (2.0–2.4) | 3.9 (3.5–4.3) | |
| Detection rate AN | ||||
| n (per 1,000 participants) | 1,390 (5.6) | 1,993 (30.2) | 1,319 (120.3) | <0.001 |
| Odds‐ratio (95% CI) | – | 5.4 (5.0–5.8)1 | 23.2 (21.5–25.1)1 | |
Note: Odds‐ratio are adjusted for age and gender.
1
Significant interaction between male and female gender (see Supporting Information).
Abbreviations: AN, advanced neoplasm; FIT, fecal immunochemical test; PPV, positive predictive value.