Table 2.
Endoscopic and histological characteristics of patients before and after Helicobacter pylori eradication
| Parameters | Before H. pylori eradication (n = 85) | After H. pylori eradication (n = 85) | P value |
| Endoscopic atrophy1, n (%) | |||
| Absent | 5 (5.9) | 4 (4.7) | 1.0 |
| Antrum | 19 (22.4) | 19 (22.4) | 1.0 |
| Antrum-predominant | 18 (21.2) | 12 (14.1) | 0.23 |
| Corpus-predominant | 21 (24.7) | 23 (27.1) | 0.73 |
| Pan-atrophy | 22 (25.9) | 27 (31.8) | 0.40 |
| OLGA-scale, n (%) | |||
| Stage 0 | 4 (4.7) | 4 (4.7) | 1.0 |
| Stage 1 | 22 (25.9) | 28 (32.9) | 0.31 |
| Stage 2 | 34 (40) | 23 (27.1) | 0.07 |
| Stage 3 | 20 (23.5) | 25 (29.4) | 0.38 |
| Stage 4 | 5 (5.9) | 5 (5.9) | 1.0 |
| EGGIM-scale, n (%) | |||
| 0-2 | 47 (55.3) | 45 (52.9) | 0.76 |
| 3-4 | 21 (24.7) | 10 (11.8) | 0.03a |
| 5-6 | 12 (14.1) | 21 (24.7) | 0.08 |
| 7-8 | 4 (4.7) | 4 (4.7) | 1.0 |
| 9-10 | 1 (1.2) | 5 (5.9) | 0.21 |
| OLGIM-scale, n (%) | |||
| Stage 0 | 40 (47.1) | 29 (34.1) | 0.08 |
| Stage 1 | 14 (16.5) | 17 (20) | 0.55 |
| Stage 2 | 14 (16.5) | 14 (16.5) | 1.0 |
| Stage 3 | 13 (15.3) | 18 (21.2) | 0.32 |
| Stage 4 | 4 (4.7) | 7 (8.2) | 0.53 |
| Gastritis at histology2, n (%) | |||
| Quiescent | 0 | 81 (95.3) | < 0.0001b |
| Mild | 19 (22.4) | 4 (4.7) | 0.001b |
| Moderate | 46 (54.1) | 0 | < 0.0001b |
| Severe | 20 (23.5) | 0 | < 0.0001b |
| MALT-hyperplasia, n (%) | |||
| Absent | 46 (54.1) | 82 (96.5) | < 0.0001b |
| Mild | 25 (29.4) | 3 (3.5) | < 0.0001b |
| Moderate | 11 (12.9) | 0 | 0.007b |
| Severe | 3 (3.5) | 0 | 0.24 |
| Histological LGD3, n (%) | |||
| Absent | 70 (82.4) | 57 (67.1) | 0.02a |
| On random biopsies | 15 (17.6) | 9 (10.6) | 0.19 |
| On random + on lesions biopsies | 0 | 6 (7) | 0.03b |
| Only on visible lesions | 0 | 13 (15.3) | 0.0001b |
Data are expressed as number of patients and percentage (in parenthesis).
1
By Kimura and Takemoto[32].
2
By Sydney System.
3
LGD: Low-grade dysplasia according to World Health Organization classification.
a
By χ2 test.
b
by Fisher’s exact test. H. pylori: Helicobacter pylori; EGGIM: Endoscopic grading of gastric intestinal metaplasia; MALT: Mucosa-associated lymphoid tissue; OLGA: Operative Link on Gastritis Assessment; OLGIM: Operative Link on Gastric Intestinal Metaplasia.