Table 3.
Comparison of autoantibodies´ positivity, ultrasonography, laboratory and clinical markers in patients with and without villous atrophy, in groups with available parameters
| Characteristics | Categories |
Villous atrophy |
||
| Yes (%) | No (%) | P value | ||
| Autoantibodies aTTG (n = 81) | Positive | 9 (50) | 9 (14.3) | 0.003b |
| Negative | 9 (50) | 54 (85.7) | ||
| Total | 18 (100) | 63 (100) | ||
| Autoantibodies aDGP (n = 78) | Positive | 14 (77.8) | 15 (25) | < 0.001b |
| Negative | 4 (22.2) | 45 (75) | ||
| Total | 18 (100) | 60 (100) | ||
| Autoantibodies aTTG IgA (n = 81) | Positive | 9 (50) | 2 (3.2) | < 0.001b |
| Negative | 9 (50) | 61 (96.8) | ||
| Total | 18 (100) | 63 (100) | ||
| Autoantibodies aTTG IgG (n = 81) | Positive | 1 (5.6) | 7 (11.1) | 0.677 |
| Negative | 17 (94.4) | 56 (88.9) | ||
| Total | 18 (100) | 63 (100) | ||
| Autoantibodies aDGP IgA (n = 78) | Positive | 13 (72.2) | 11 (18.3) | < 0.001b |
| Negative | 5 (27.8) | 49 (81.7) | ||
| Total | 18 (100) | 60 (100) | ||
| Autoantibodies aDGP IgG (n = 78) | Positive | 11 (61.1) | 9 (15) | < 0.001b |
| Negative | 7 (38.9) | 51 (85) | ||
| Total | 18 (100) | 60 (100) | ||
| Ultrasonography (n = 66) | Positive | 11 (64.7) | 13 (26.5) | 0.008b |
| Negative | 6 (35.3) | 36 (73.5) | ||
| Total | 17 (100) | 49 (100) | ||
| Diarrhea (n = 81) | Yes | 8 (44.4) | 11 (17.5) | 0.027a |
| No | 10 (55.6) | 52 (82.5) | ||
| Total | 18 (100) | 63 (100) | ||
| Yes | 4 (22.2) | 4 (6.4) | 0.068 | |
| Weight loss (n = 81) | No | 14 (77.8) | 59 (93.6) | |
| Total | 18 (100) | 63 (100) | ||
| Abdominal pain (n = 81) | Yes | 3 (16.7) | 14 (22.2) | 0.751 |
| No | 15 (83.3) | 49 (77.8) | ||
| Total | 18 (100) | 63 (100) | ||
| Anemia (n = 80) | Positive | 1 (5.6) | 8 (12.9) | 0.676 |
| Negative | 17 (94.4) | 54 (87.1) | ||
| Total | 18 (100) | 62 (100) | ||
| Sideropenia (n = 80) | Positive | 4 (22.2) | 18 (29) | 0.766 |
| Negative | 14 (77.8) | 44 (71) | ||
| Total | 18 (100) | 62 (100) | ||
| Vitamin D deficiency (n = 80) | Positive | 8 (44.4) | 9 (14.5) | 0.018a |
| Negative | 10 (55.6) | 53 (85.5) | ||
| Total | 18 (100) | 62 (100) | ||
a
P < 0.05.
b
P < 0.01. aTTG: Anti-tissue transglutaminase antibodies; aDGP: Anti-deamidated gliadin peptide antibodies.