Table 6.
Sensitivity, specificity, positive and negative predictive value of bowel ultrasonography, clinical and laboratory markers for prediction of villous atrophy in patients with celiac disease
| Characteristics | Sensitivity (%) (95%CI) | Specificity (%) (95%CI) | Accuracy (%) (95%CI) | Positive predictive value (%) (95%CI) | Negative predictive value (%) (95%CI) |
| Ultrasonography | 64.7 (38.3-85.8) | 73.5 (58.9-85.1) | 71.2 (58.8-81.7) | 45.8 (32.1-60.3) | 85.7 (75.5-92.1) |
| Diarrhea | 44.4 (21.5-69.2) | 82.5 (70.9-91.0) | 74.1 (63.1-83.2) | 42.1 (25.7-60.5) | 83.9 (77.2-88.9) |
| Weight loss | 22.2 (6.4-47.6) | 93.7 (84.5-98.2) | 77.8 (67.2-86.3) | 50.0 (21.7-78.3) | 80.8 (76.6-84.5) |
| Abdominal pain | 16.7 (3.6-41.4) | 77.8 (65.5-87.3) | 64.2 (52.8-74.6) | 17.7 (6.5-39.9) | 76.6 (71.9-80.7) |
| Anemia | 5.6 (0.1-27.3) | 87.1 (76.2-94.3) | 68.8 (57.4-78.7) | 11.1 (1.6-48.3) | 76.1 (73.3-78.6) |
| Sideropenia | 22.2 (6.4-47.6) | 71.0 (58.1-81.8) | 60.0 (48.4-70.8) | 18.2 (7.9-36.4) | 75.9 (70.1-80.8) |
| Vitamin D deficiency | 44.4 (21.5-69.2) | 85.5 (74.2-93.1) | 76.3 (65.4-85.1) | 47.1 (28.7-66.3) | 84.1 (77.6-89.0) |
CI: Confidence interval.