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. 2020 Apr 30;59(30):12321–12325. doi: 10.1002/anie.202003392

Scheme 1.

Scheme 1

Metalation of benzofuran (1 a) with KDA/TMEDA and subsequent trapping with adamantanone (2 a) in continuous flow. [a] Isolated yield of analytically pure product. [b] Cyclohexane was used as solvent.