Scheme 1.

Metalation of benzofuran (1 a) with KDA/TMEDA and subsequent trapping with adamantanone (2 a) in continuous flow. [a] Isolated yield of analytically pure product. [b] Cyclohexane was used as solvent.

Metalation of benzofuran (1 a) with KDA/TMEDA and subsequent trapping with adamantanone (2 a) in continuous flow. [a] Isolated yield of analytically pure product. [b] Cyclohexane was used as solvent.