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. 2020 Apr 30;59(30):12321–12325. doi: 10.1002/anie.202003392

Scheme 2.

Scheme 2

Metalation of 3‐methoxybenzonitrile (1 k) with KDA/TMEDA in continuous flow and subsequent trapping with various electrophiles. [a] Yield of analytically pure isolated product. [b] Yield of analytically pure isolated product obtained under batch conditions.