. 2020 May 6;30(4):811–830. doi: 10.1111/bpa.12843

Table 3.

Demographic and pathological features of all cases with or without GFAs

	Frontal cortex (N = 105)		Caudate nucleus (N = 105)		Putamen (N = 105)		Amygdala (N = 96)
	Cases with GFAs	Cases without GFAs	Cases with GFAs	Cases without GFAs	Cases with GFAs	Cases without GFAs	Cases with GFAs	Cases without GFAs
N (%)	36 (34.3)	69 (65.7)	35 (33.3)	70 (66.7)	39 (37.1)	66 (62.9)	43 (44.8)	53 (55.2)
Age at death [y, mean ± SD] ^†	74.8 ± 11.5	69.2 ± 12.2	75.7 ± 10.5^*	68.8 ± 12.4	77.2 ± 9.6^*	67.5 ± 12.2	73.7 ± 10.3	69.2 ± 13.5
Braak stage [median (25^th percentile, 75^th percentile)] ^†	2 (2, 4)	2 (1, 5)	3 (2, 4)	2 (1, 5)	3 (2, 4)	2 (1, 4.75)	2 (2, 4)	3 (1, 5)
Thal phase [median (25^th percentile, 75^th percentile)] ^†	1 (0, 3)	0 (0, 3)	1 (0, 3)	0 (0, 3)	1 (0, 3)	0 (0, 3)	1 (0, 3)	1 (0, 4)
AGD stage [median (25^th percentile, 75^th percentile)] ^†	0 (0, 2)	0 (0, 0)	0 (0, 2)^*	0 (0, 0)	0 (0, 2)^*	0 (0, 0)	1 (0, 2)^*	0 (0, 0)
PSP (N, %) ^‡	9 (90.0)^*	1 (10.0)	10 (100.0)^*	0 (0.0)	10 (100.0)^*	0 (0.0)	9 (100.0)^*	0 (0.0)
CBD (N, %) ^‡	1 (14.3)	6 (85.7)	1 (14.3)	6 (85.7)	1 (14.3)	6 (85.7)	1 (16.7)	5 (83.3)
LBD (N, %) ^‡	7 (28.0)	18 (72.0)	9 (36.0)	16 (64.0)	9 (36.0)	16 (64.0)	7 (30.4)	16 (69.6)
TDP‐43 pathology (N, %) ^‡	11 (32.4)	23 (67.6)	14 (41.2)	20 (58.8)	14 (41.2)	20 (58.8)	12 (35.3)	22 (64.7)
PART only (N, %) ^‡ ^, ^§	2 (40.0)	3 (60.0)	0 (0.0)	5 (100.0)	1 (20.0)	4 (80.0)	3 (75.0)	1 (25.0)

Abbreviations: AGD = argyrophilic grain disease; CBD = corticobasal degeneration; GFA = granular/fuzzy astrocyte; LBD = Lewy body disease; PSP = progressive supranuclear palsy; TDP‐43 pathology = all cases having FTLD‐TDP, ALS‐TDP and other TDP‐43‐positive lesions in the limbic system and neocortex are included.

P < 0.01.

^{^†}

Mann–Whitney U test.

^{^‡}

Frequency of each lesion was compared using Fisher’s exact test.

^{^§}

PART cases without any other tauopathies and non‐tauopathies. The amygdala was not available in one of these PART cases.