Table 4.
Ordered logistic regression analyses of associations between density of GFAs, age, Braak stage, Thal phase, PSP and AGD by anatomical region in all subjects
| Odds ratio | 95% confidence interval | P‐value | |
|---|---|---|---|
| GFAs in the frontal cortex | |||
| Age at death | 1.03 | 0.98–1.08 | 0.325 |
| Braak stage | 1.27 | 0.90–1.79 | 0.171 |
| Thal phase | 0.87 | 0.63–1.20 | 0.391 |
| PSP | 214.19 | 29.16–1573.46 | <0.001* |
| AGD | 7.30 | 2.31–23.04 | <0.001* |
| GFAs in the caudate nucleus | |||
| Age at death | 1.02 | 0.96–1.07 | 0.582 |
| Braak stage | 1.54 | 1.02–2.32 | 0.038 |
| Thal phase | 1.07 | 0.77–1.49 | 0.686 |
| PSP | 483.92 | 56.76–4125.91 | <0.001* |
| AGD | 14.68 | 3.69–58.41 | <0.001* |
| GFAs in the putamen | |||
| Age at death | 1.07 | 1.01–1.13 | 0.022 |
| Braak stage | 1.67 | 1.10–2.54 | 0.015 |
| Thal phase | 0.84 | 0.60–1.17 | 0.293 |
| PSP | 1020.11 | 96.40–10795.50 | <0.001* |
| AGD | 15.66 | 3.98–61.65 | <0.001* |
| GFAs in the amygdala | |||
| Age at death | 1.00 | 0.95–1.06 | 0.947 |
| Braak stage | 1.14 | 0.81–1.61 | 0.454 |
| Thal phase | 0.73 | 0.51–1.05 | 0.093 |
| PSP | 52.95 | 9.32–300.92 | <0.001* |
| AGD | 118.14 | 23.48–594.39 | <0.001* |
*
P < 0.01.
Abbreviations: AGD = the presence of AGD lacking any other primary tauopathies; GFA = granular/fuzzy astrocyte; PSP = the presence of PSP lacking any other primary tauopathies.