Table 1. Kinetic Binding Constants for the Interaction between PSMA and the NBs, As Measured by SPRa.
| NB | Kon [M–1 s–1] | Koff [s–1] | KD [nM] |
|---|---|---|---|
| NB7 | (7.1 × 105) ± (4.5 × 102) | (3.9 × 10–5) ± (2.8 × 10–7) | 0.055 |
| NB8 | (2.0 × 104) ± (4.2 × 101) | (1.2 × 10–4) ± (5.3 × 10–7) | 6.0 |
| NB13 | (3.6 × 104) ± (8.9 × 101) | (2.2 × 10–5) ± (9.9 × 10–7) | 0.60 |
| NB37 | (2.2 × 104) ± (5.3 × 101) | (7.5 × 10–5) ± (6.6 × 10–7) | 3.4 |
Values represent the mean ± SD.