Table 1.
Characteristics of patients with APA and EH at diagnosis
| EH | APA | P value | |
| (n=41) | (n=100) | ||
| Male | |||
| Female (%) | 24 (58.5) | 58 (58.0) | 0.999 |
| Male(%) | 17 (41.5) | 42 (42.0) | |
| Age (years) | 53.1±12.4 | 49.3±11.8 | 0.090 |
| Waist circumference (cm) | 84.1±11.6 | 81.1±10.4 | 0.167 |
| BMI (kg/m2) | 24.9±3.6 | 25.0±3.8 | 0.919 |
| sBP (mm Hg) | 151.0±17.5 | 154.1±22.9 | 0.735 |
| Log ald (ng/dL) | 3.4±0.7 | 3.9±0.6 | <0.001 |
| Log renin (ng/mL/hour) | −0.5±1.1 | −1.9±1.9 | <0.001 |
| Log (ARR) (ng/dL per ng/mL/hour) |
3.9±1.4 | 5.8±2.0 | <0.001 |
| Potassium (mmol/L) | 4.2±0.4 | 3.6±0.7 | <0.001 |
| Cholesterol (mg/dL) | 192.4±33.4 | 190.2±34.0 | 0.671 |
| Triglyceride (mg/dL) | 108.4±58.1 | 125.4±120.2 | 0.938 |
| HOMA-IR index | 3.2±6.0 | 2.6±4.5 | 0.152 |
| eGFR (mL/min/1.73 m2) | 90.3±28.0 | 86.8±29.4 | 0.409 |
| Duration of HTN (years) | 5.8±6.3 | 7.8±7.6 | 0.100 |
| Log VFA (mm2) | 9.3±0.5 | 9.1±0.5 | 0.021 |
| Log SFA (mm2) | 9.8±0.4 | 9.7±0.4 | 0.117 |
Data are expressed as mean±SD unless otherwise indicated.
APA, aldosterone-producing adenoma; ARR, aldosterone–renin ratio; BMI, body mass index; eGFR, estimate glomerular filtration rate; EH, essential hypertension; HOMA-IR, homeostasis model assessment for insulin resistance; HTN, hypertension; sBP, systolic blood pressure; SFA, subcutaneous fat area; VFA, visceral fat area.