Table 3.
Characteristics of patients with APA at diagnosis categories by hypertensive status after adrenalectomy
| All patients (n=100) |
Residual of hypertension (n=34) |
Cure of hypertension (n=66) |
P values | |
| Female (%) | 58 (58.0%) | 13 (38.2%) | 45 (68.2%) | 0.005 |
| Male (%) | 42 (42.0%) | 21 (61.8%) | 21 (31.8%) | 0.005 |
| Age (years) | 49.3±11.8 | 53.3±12.4 | 47.3±11.1 | 0.016 |
| Waist circumference (cm) | 81.1±10.4 | 86.4±10.4 | 78.4±9.4 | <0.001 |
| BMI (kg/m2) | 25.0±3.8 | 26.1±3.5 | 24.5±3.8 | 0.012 |
| sBP (mm Hg) | 154.1±22.9 | 156.1±21.8 | 153.1±23.5 | 0.298 |
| Log ald (ng/dL) | 3.9±0.6 | 3.8±0.6 | 4.0±0.6 | 0.352 |
| Log renin (ng/mL/hour) | −1.9±1.9 | −1.9±2.1 | −1.9±1.8 | 0.924 |
| Log (ARR) (ng/dL per ng/mL/hour) |
5.8±2.0 | 5.7±2.1 | 5.9±2.0 | 0.859 |
| Potassium (mmol/L) | 3.6±0.7 | 3.8±0.5 | 3.5±0.7 | 0.018 |
| Cholesterol (mg/dL) | 190.2±34.0 | 190.1±32.9 | 190.3±34.9 | 0.839 |
| Triglyceride (mg/dL) | 125.4±120.2 | 124.8±67.1 | 125.7±140.4 | 0.123 |
| HOMA-IR index | 2.6±4.5 | 3.2±5.7 | 2.4±3.7 | 0.184 |
| eGFR (mL/min/1.73 m2) | 86.8±29.4 | 75.4±27.0 | 92.6±29.0 | 0.002 |
| Duration of HTN (years) | 7.8±7.6 | 10.4±7.6 | 6.4±7.3 | 0.004 |
| Log VFA (mm2) | 9.1±0.5 | 9.4±0.4 | 8.9±0.5 | <0.001 |
| Log SFA (mm2) | 9.7±0.4 | 9.8±0.3 | 9.6±0.4 | 0.070 |
Data are expressed as mean±SD unless otherwise indicated.
APA, aldosterone-producing adenoma; ARR, aldosterone-renin ratio; BMI, body mass index; eGFR, estimate glomerular filtration rate; HOMA-IR, homeostasis model assessment for insulin resistance; HTN, hypertension; sBP, systolic blood pressure; SFA, subcutaneous fat area; VFA, visceral fat area.