Table 3.
Expression of pATM, pChk2, and p53 in Relation to Local Recurrence Separately for Glottic (n = 22) and Supraglottic (n = 12) Location.
| Glottic (n = 93) | Supraglottic (n = 48) | |||||
|---|---|---|---|---|---|---|
| Characteristics | No. of Patients With Local Recurrence (%) | Univariable HR (95% CI) | P | No. of Patients With Local Recurrence (%) | Univariable HR (95% CI) | P |
| pATM | ||||||
| Low | 19/82 (23.2) | 1 | 1/21 (4.8) | 1 | ||
| High | 3/11 (27.3) | 1.06 (0.31–3.57) | .93 | 11/27 (40.7) | 10.9 (1.40–84.4) | .02* |
| pChk2 | ||||||
| Low | 22/93 (23.7) | — | — | 9/43(20.9) | 1 | |
| High | 0/0 | — | 3/5 (60) | 3.13 (0.85–11.6) | .09 | |
| p53 | ||||||
| Low | 2/9 (22.2) | 1 | 0/2 (0) | 1 | ||
| High | 10/44 (22.7) | 1.07 (0.24–4.90) | .93 | 4/21 (19.0) | 23.55 (<0.001–>1,000) | .67 |
CI = confidence interval; HR = hazard ratio; N = node; T = tumor.
*
Signifies statistically significant relation.