Figure 5.

DHA deficiency does not alter behavioral functions. A, Individual exploration trajectories showing the change in the exploratory activity of WT and KO mice. Brown lines indicate locomotion (horizontal movements), blue lines indicate rears (vertical movements), and green lines indicate center area and corners. Exploratory activity was calculated as the number of visits to the center zone, percentage of time spent in the center zone, and percentage of distance in the center zone. Data are shown as mean ± SEM of 12 WT and 16 KO mice and analyzed by the unpaired Student's t test. B, Working memory consolidation with two objects (novel and familiar) evaluated as the percentage of time spent at exploring the objects. Data are shown as mean ± SEM of seven animals per group (WT and KO) and analyzed by the unpaired Student's t test. C, Spatial and learning memory evaluated as the ability of animals to seek out for escape holes (time spent in quadrants of target, opposite, negative or positive holes). Data are shown as mean ± SEM of 8 WT and 7 KO and analyzed by the unpaired Student's t test