Table 1.

Association of Deleterious PALB2 Mutations With Breast Cancer Risk

	Total, No.	Deleterious PALB2 Mutation Frequency, No.	Prevalence, %	OR (95% CI)	P
Healthy controls	5890	11	0.19	1.00 (reference)
Patients with breast cancer	16,501	160	0.97	5.23 (2.84‐9.65)	<.0001
Age group
≤30 y	593	11	1.85	10.09 (3.95‐25.79) a	<.0001
>30 y	15,883	149	0.94	5.06 (2.74‐9.34)	<.0001

Abbreviations: CI, confidence interval; OR, odds ratio; PALB2, partner and localizer BRCA2.

^aFisher exact test.