Table 2.

Infectious manifestation and immunological characteristics (n = 2)

Patient	Recurrent infections										Treatment with IVIG	Serum Ig levels (g/L)			Antibody titers against S pneumoniae
	Skin		Resp tract		ENT		Gastrointestinal		Severe invasive			IgM (0.45‐2.3)a	IgG (7.0‐16.0)a	IgA (0.76‐3.91)a
	≤6 y	>6 y	≤6 y	>6 y	≤6 y	>6 y	≤6 y	>6 y	≤6 y	>6 y
1	Yes	Yes	—	—	—	—	—	—	—	—	—	0.52	22.0	5.70	Low
2		Yes	—	Yes	Yes	Yes	—	—	‐	—	—	1.98	11.0	2.82	Low
3	Yes	Yes	—	—	Yes	‐	—	—	‐	—	—	1.19	7.0	2.54	n.d.
4	Yes	Yes	—	—	Yes	‐	Yes	—	‐	—	—	0.97	12.2	1.80	Normal
5	Yes	‐	Yes	—	Yes	Yes	—	—	Yes	—	—	0.97	13.9 b	1.84	n.d.
6	Yes	Yes	—	—	—	—	—	—	‐	—	—	0.92	9.6	1.24	Low
7	Yes	Yes	—	—	Yes	—	—	—	‐	—	Yes	1.36	16.8	2.11	Low
8	—	—	—	—	‐	—	—	—	‐	—	—	0.34	12.4	2.35	Low
9	Yes	Yes	—	—	‐	—	—	—	‐	—	—	0.47	13.7	3.87	Low
10	Yes	Yes	—	—	‐	—	—	—	‐	—	Yes	0.67	10.7	1.81	Low
11	Yes	Yes	—	—	Yes	Yes	—	—	‐	—	—	1.13	12.2	1.53	Low
12	Yes	—	—	—	Yes	‐	—	—	‐	—	—	0.26	14.2	1.71	Low
13	Yes	—	—	—	—	—	—	—	‐	—	—	n.d.	n.d.	n.d.	n.d.
14	—	Yes	Yes	—	—	—	—	—	‐	—	—	0.51	9.0	1.89	Low

Values below the normal range are depicted in bold font; above normal range in italics.

Abbreviation: n.d., not determined.

^aNormal values for adults.

^bNormal values children aged 5‐10 y are IgM 0.3‐1.8 g/L, IgG 5.0‐13.0 g/L, and IgA 0.5‐2.3 g/L.