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Changes with age of cognition, muscle wasting, and serum alpha‐fetoprotein (AFP) in individuals with Primrose syndrome. A, Cognition. No evident correlation. B, Muscle wasting; data are presented based on age of first appearance. Increase with age evident. C, AFP serum levels. Each symbol represents a single individual; course over time in single patients is depicted if available. Elevated levels in almost every individual; no clear change with age in a single individual
