Table 1.
Diagnostic methods of Helicobacter pylori infection and their implementation rate between April 2008 and October 2016
| Methods of diagnosis | Number of patients who received eradication therapy | Combined proportion, % |
|---|---|---|
| Before both primary and secondary eradication therapy | ||
| Urea breath test | 60,750 | 27.5 |
| Antibody measurement1 | 57,299 | 25.9 |
| Rapid urease test | 48,250 | 21.8 |
| Antibody measurement (qualitative)2 | 22,432 | 10.1 |
| Stool antigen test | 8,585 | 3.9 |
| Microbial culture | 7,908 | 3.6 |
| Rapid urease test and direct microscopic count | 4,991 | 2.3 |
| Direct microscopic count | 4,971 | 2.2 |
| Direct microscopic count and microbial culture | 1,081 | 0.5 |
| Direct microscopic count and antibody measurement | 970 | 0.4 |
| Rapid urease test and antibody measurement | 564 | 0.3 |
| Direct microscopic count and urea breath test | 494 | 0.2 |
| Antibody measurement and urea breath test | 481 | 0.2 |
| Direct microscopic count and antibody measurement (qualitative) | 476 | 0.2 |
| Antibody measurement (qualitative) and urea breath test | 441 | 0.2 |
| Urea breath test and stool antigen test | 331 | 0.1 |
| Rapid urease test and microbial culture | 249 | 0.1 |
| Antibody measurement and stool antigen test | 141 | 0.1 |
| Microbial culture and antibody measurement | 132 | 0.1 |
| Rapid urease test and antibody measurement (qualitative) | 119 | 0.1 |
| Other tests | 507 | 0.2 |
| Total | 221,172 | 100.0 |
| After both primary and secondary eradication therapy | ||
| Urea breath test | 212,759 | 89.6 |
| Stool antigen test | 18,146 | 7.6 |
| Antibody measurement1 | 1,571 | 0.7 |
| Urea breath test and stool antigen test | 1,551 | 0.7 |
| Rapid urease test | 924 | 0.4 |
| Direct microscopic count | 755 | 0.3 |
| Antibody measurement (qualitative)2 | 479 | 0.2 |
| Microbial culture | 279 | 0.1 |
| Antibody measurement and urea breath test | 262 | 0.1 |
| Direct microscopic count and urea breath test | 234 | 0.1 |
| Rapid urease test and direct microscopic count | 181 | 0.1 |
| Other tests | 206 | 0.1 |
| Total | 237,347 | 100.0 |
1
Antibody measurement: it was measured with an apparatus (the latex agglutination method and enzyme immunoassay method).
2
Antibody measurement (qualitative): it is possible to measure by visual observation (the immunochromatography method and gold colloidal method).