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. 2020 Mar 26;27(3):163–173. doi: 10.1159/000506698

Table 1.

IRIS stage from the International Renal Interest Society (IRIS)

IRIS stage Creatinine, mg/dL Comment
At risk <1.6 Predisposing parameters
1 <1.6 Nonazotemic, some other renal abnormalities present
2 1.6–2.8 Mild renal azotemia
3 2.9–5.0 Moderate renal azotemia
4 >5.0 Risk of systemic clinical signs and uremic crisis
IRIS substage UP/C value Comment
1 <0.2 Nonproteinuric
2 0.2–0.4 Borderline proteinuric
3 >0.4 Proteinuric
IRIS substage Systolic blood pressure, mm Hg Comment
1 <140 Normotensive
2 140–159 Prehypertensive
3 160–179 Hypertensive
4 ≥180 Severely hypertensive