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. Author manuscript; available in PMC: 2020 Jul 27.
Published in final edited form as: Am J Clin Pathol. 2011 Jun;135(6):890–900. doi: 10.1309/AJCPV2D1DDSGJDBW

▮Table 2▮.

Comparison of GS-1 and GS-2 in Cases Demonstrating TCR-Vβ Restriction*

Diagnosis/Case No. TCR−Vβ Family GS−1: Vβ−Restricted Gated Cells (%) GS−2: Vβ−Restricted Gated Cells (%) Clonality by
TCR PCR
ATLL
 3 8 30.16 60.49 +
 6 9 54.54 58.32 +
 7 22 86.45 89.13 +
 8 17 18.4 77.46 +
 10 1 28.49 84.53 +
 11 1 9.2 67.86 +
 12 1 54.42 82.84 +
 14 22 69.09 81.83 +
 15 18 86.04 92.06 +
 16 17 95.45 98.23 +
 17 5.1 98.02 +
 19 17 53.6 70.75 +
 21 5.1 87.91 98.37 +
 22 9 6.72 63.05 +
 24 13.1 80.19 83.56 ND
CTCL
 26 21.3 91.71 97.91 +
 28 8 92.02 98.60 +
 29 14 99.31 ND
 30 13.2 87.0 92.70 +
 31 20 97.78 ND
PTCL
 32 4 53.06 86.67 +
 33 17 80.94 98.68 +
 34 17 91.27 95.15 +
TPLL
 35 13.1 93.79 98.00 +
LGL
 36 3 63.58 +
 39 7.1 98.45 +
 40 8 97.49 +

ATLL, human T-lymphotropic virus-1–associated adult T-cell leukemia/lymphoma; CTCL, cutaneous T-cell lymphoma; GS-1, gating strategy 1; GS-2, gating strategy 2; LGL, T-cell large granular lymphocytic leukemia; ND, not done; PCR, polymerase chain reaction; PTCL, peripheral T-cell lymphoma, not otherwise specified; TCR, T-cell receptor; TPLL, T-cell prolymphocytic leukemia; +, TCR clonal rearrangement detected.

*

Mean (range) for GS-1, 70.6% (6.72%−99.31%); and for GS-2, 84.6% (58.32%−98.68%).

All CD4+ or CD8+ T cells are neoplastic, and GS-2 is not applicable.

No apparent aberrancy in T-cell antigen expression detected, and GS-2 is not applicable.