HFD does not affect NLRP3 or ASC transcriptional priming. a Expression of NLRP3 protein, normalized to γ-tubulin, and b
Nlrp3 mRNA, normalized to ribosomal 18S, and c expression of ASC protein and d
Pycard (ASC) mRNA, in LV lysates of wild-type (WT) mice fed an HFD or standard chow for 8 weeks (n = 6 each). Data show mean ± SD, relative to chow. *P < 0.05 vs. chow