Type 2 diabetes increases PAR4 expression in human atrial tissue. a PAR1, b PAR2 and c PAR4 protein expression, normalized to γ-tubulin, in lysates of right atrial appendages from non-diabetic control patients (Ctl, n = 13) and patients with type 2 diabetes mellitus (DM, n = 15). Data show mean ± SD, relative to Ctl. *P < 0.05 vs. Ctl