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. Author manuscript; available in PMC: 2020 Jul 27.
Published in final edited form as: Methods Cell Biol. 2019 Jan 2;151:127–158. doi: 10.1016/bs.mcb.2018.11.018

Table 1.

Comparison of single cell sequencing platforms and costs (modified from (Ziegenhain et al., 2017))

Method Cell Number per Group* Minimal Cost ($)
CEL-seq2/C1 85/100/110 ~2,420/2,310/2,250
Drop-seq 99/135/254 ~1,010/700/690
MARS-seq 110/135/160 ~1,380/1,030/820
SCRB-seq 64/90/166 ~900/810/1,080
Smart-seq/C1 150/172/215 ~9,010/9,440/11,290
Smart-seq2 (commercial Tn5) 95/105/128 ~10,470/11,040/13,160
Smart-seq2 (in-house Tn5) 95/105/128 ~1,520/1,160/1,090
*

Cell groups listed for sequencing depth of 1, 0.5, and 0.25 million reads.