Table 3.
Characteristics of patients from 12 published studies and our cohort study included in the meta-analysis.
| Study | All patients |
Non-severe |
Severe |
|||||
|---|---|---|---|---|---|---|---|---|
| Sample size | D-dimer (μg/ml) | Sample size | D-dimer (μg/ml) | No. of abnormal D-dimer | Sample size | D-dimer (μg/ml) | No. of abnormal D-dimer | |
| Cao M et al. [10] | 195 | 0.39(0.28–0.67) | 176 | 0.37(0.26–0.56) | NA | 19 | 0.77(0.43–1.23) | NA |
| Liu J et al. [11] | 40 | 0.6(0.3–0.9) | 27 | 0.4(0.2–0.8) | NA | 13 | 0.9(0.7–1.5) | NA |
| Liu L et al. [12] | 51 | 0.28(0.19–0.51) | 44 | 0.28(0.18–0.46) | NA | 7 | 0.6(0.28–1.4) | NA |
| Lu HZ et al. [13] | 265 | 0.42(0.29–0.8) | 243 | 0.39(0.28–0.72) | NA | 22 | 0.8(0.5–3.5) | NA |
| Qian GQ et al. [14] | 91 | 0.3(0.11–0.45) | 82 | 0.3(0.11–0.4) | NA | 9 | 0.45(0.16–0.49) | NA |
| Xu Y et al. [15] | 69 | 0.5(0.3–1.2) | 44 | 0.5(0.3–0.9) | NA | 25 | 2.3(0.6–14.1) | NA |
| Zhang GQ et al. [16] | 221 | 0.23(0.13–0.49) | 166 | 0.18(0.12–0.32) | NA | 55 | 0.44(0.21–1.30) | NA |
| Zhang JJ et al. [17] | 81 | 0.2(0.1–0.5) | 43 | 0.2(0.1–0.3) | NA | 38 | 0.4(0.2–2.4) | NA |
| Chen X et al. [18] | 254 | NA | 209 | NA | 199 | 45 | NA | 44 |
| Guan W et al. [3] | 560 | NA | 451 | NA | 195 | 109 | NA | 65 |
| Liu T et al. [19] | 80 | NA | 11 | NA | 0 | 69 | NA | 45 |
| Qi D et al. [20] | 267 | NA | 217 | NA | 6 | 50 | NA | 13 |
| Our study | 1561 | 0.7(0.33–1.61) | 1196 | 0.52(0.28–1.13) | 621 | 365 | 1.77(0.86–4.55) | 327 |
Data of D-dimer value were shown in median (IQR). IQR = interquartile range.