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. Author manuscript; available in PMC: 2021 Mar 5.
Published in final edited form as: J Neuroendocrinol. 2020 Mar 5;32(3):e12839. doi: 10.1111/jne.12839

Figure 8. Preincubation of PVN slices in 200 nM oxytocin produces an Oxtr dependent increase in holding current and current density.

Figure 8.

A) Slices incubated 200 nM oxytocin for a minimum of one hour prior to whole-cell recording were compared to control slices from the same animals incubated in normal ACSF. Results indicated that preincubation in 200 nM oxytocin produced a clear increase in holding current and current density relative to preparation matched controls. Asterisks indicated P<0.05, see text in the results section for further details. B) The effects produced by preincubation of slices in 200 nM oxytocin presented in panel A were not observed in slices that were incubated in 200 nM oxytocin + 1 μM L-368. This result highlights a clear role for Oxtr(s) in producing the inhibitory effect of preincubation highlighted in panel A. See text of the results for further details.