. Author manuscript; available in PMC: 2021 Jun 15.

Published in final edited form as: Am J Nephrol. 2020 Jun 15;51(6):473–479. doi: 10.1159/000508051

Table 1.

Baseline characteristics based on having a baseline uKIM-1/Cr above (high uKIM-1/Cr) or below (low uKIM-1/Cr) the median value of 0.2417 pg/g, as well as the combined baseline characteristics for the cohort.

Variables	High uKIM-1/Cr N=377	Low uKIM-1/Cr N=377	P-value
Age (years), Mean ± SD	43±10	43±10	.715
Early ADPKD (Study A), n (%)	184 (48.8)	226 (59.9)	.002
Treatment Group, n (%)	180 (47.7)	194 (51.5)	.308
Male Gender, n (%)	170 (45.1)	201 (53.3)	.024
PKD 1 genotype, n (%)	287 (76.1)	294 (78.0)	.544
Systolic BP (mmHg), Mean ± SD	127.6 ± 15.0	128.1 ± 13.9	.668
Diastolic BP (mmHg), Mean ± SD	80.0 ± 10.7	79.4 ± 10.0	.399
BMI (kg/m²), Mean ± SD	27.7 ± 5.0	27.5 ± 5.0	.557
Estimated GFR (mL/min/1.73 m²), Mean ± SD	69.8 ± 25.9	73.6 ± 24.8	.039
uACR (mg/g), median (IQR)	0.02 (0.01–0.05)	0.02(0.01–0.03)	<.001
uKIM-1/Cr (pg/g), median (IQR)	0.50 (0.34–0.75)	0.12 (0.07–0.18)	<.001

ADPKD, autosomal dominant polycystic kidney disease; BP, blood pressure; BMI, body mass index; GFR, glomerular filtration rate; uACR, urinary albumin-to-creatinine ratio; uKIM-1, urinary kidney injury molecule 1. The P values were calculated based on the chi-square test for categorical variables, rank sum test for uACR and uKIM-1/Cr, and t-test for other continuous variables.