Table 2.
Difference in annual decline in eGFR in patients with uKIM-1/Cr above (high uKIM-1/Cr) or below (low uKIM-1/Cr) the median value of 0.2417 pg/g.
Model | Difference in annual change in eGFR (mL/min), high versus low uKIM-1/Cr | p-value |
---|---|---|
Unadjusted | −0.64 | <.001 |
Model 1 | −0.58 | <.001 |
Model 2 | −0.56 | <.001 |
Model 3 | −0.47 | .002 |
Model 1: Treatment group (Treatment vs Control), Study (A vs B)
Model 2: variables in model 1 + age, gender
Model 3: variables in model 2 + baseline systolic BP, baseline diastolic BP, baseline BMI, PKD genotype, and baseline uACR