Table 3.

Difference in annual eGFR change in patients with uKIM-1/Cr above (high uKIM-1/Cr) or below (low uKIM-1/Cr) the median value of 0.2417 pg/g, in patients in study A and B separately.

	Study A		Study B
Model	Difference in annual change in eGFR (mL/min), high versus low uKIM-1/Cr	p-value	Difference in annual change in eGFR (mL/min), high versus low uKIM-1/Cr	p-value
Unadjusted	−0.54	.02	−0.62	.001
Model 1	−0.55	.02	−0.62	.001
Model 2	−0.56	.02	−0.53	.003
Model 3	−0.42	.06	−0.45	.009

Model 1: Treatment group (Treatment vs Control)

Model 2: variables in model 1 + age, gender

Model 3: variables in model 2 + baseline systolic BP, baseline diastolic BP, baseline BMI, PKD genotype, and baseline uACR