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. 2020 Jul 27;15(7):e0235663. doi: 10.1371/journal.pone.0235663

Table 2. GINI importance of features from MRI eigenvectors and plasma BMs.

Feature Coefficient Feature Coefficient
ADNI_Compressed Executive Function 0.1153 Apolipoprotein H (ugmL) 0.03112
Apolipoprotein E (ug/ml) 0.0855 VSBPSYS (systolic BP) 0.03087
ADNI_Compressed Memory 0.0801 Apolipoprotein Aiv (ug/ml) 0.03077
CReactiveProtein (ug/mL) 0.0666 Insulin (U/mL) 0.03057
Apolipoprotein D (ug/ml) 0.0453 Age (yrs) 0.02962
BMI 0.0440 Leptin (ng/mL) 0.02950
MRI Eigen Vector #4 0.0380 Vitronectin (ug/ml) 0.02869
Apolipoprotein B (ug/ml) 0.0362 MRI Eigen Vector #3 0.02839
Apolipoprotein Ci (ng/ml) 0.0352 MRI Eigen Vector #1 0.02728
Apolipoprotein Aii (ng/ml) 0.0346 MRI Eigen Vector #2 0.02575
Apolipoprotein Ciii (ug/ml) 0.0341 Gender 0.02426
Apolipoprotein Ai (mg/ml) 0.0333 Testosterone (ng/ml) 0.002845
MRI Eigen Vector #5 0.0324

lists in order of decreasing coefficient size the features in order of the diminishing of their importance. Among the top 7 most important features are the composite executive function (EF) score and composite memory (Mem), an MRI eigenvector, 3 plasma biomarkers and a demographic. EV#4 includes: L. accumbens vol, R. ventral dorsal column vol, L. & R. amygdala vol, L. & R. hippocampal vol, R. entorhinal vol.