Table 2. GINI importance of features from MRI eigenvectors and plasma BMs.
Feature | Coefficient | Feature | Coefficient |
---|---|---|---|
ADNI_Compressed Executive Function | 0.1153 | Apolipoprotein H (ugmL) | 0.03112 |
Apolipoprotein E (ug/ml) | 0.0855 | VSBPSYS (systolic BP) | 0.03087 |
ADNI_Compressed Memory | 0.0801 | Apolipoprotein Aiv (ug/ml) | 0.03077 |
CReactiveProtein (ug/mL) | 0.0666 | Insulin (U/mL) | 0.03057 |
Apolipoprotein D (ug/ml) | 0.0453 | Age (yrs) | 0.02962 |
BMI | 0.0440 | Leptin (ng/mL) | 0.02950 |
MRI Eigen Vector #4 | 0.0380 | Vitronectin (ug/ml) | 0.02869 |
Apolipoprotein B (ug/ml) | 0.0362 | MRI Eigen Vector #3 | 0.02839 |
Apolipoprotein Ci (ng/ml) | 0.0352 | MRI Eigen Vector #1 | 0.02728 |
Apolipoprotein Aii (ng/ml) | 0.0346 | MRI Eigen Vector #2 | 0.02575 |
Apolipoprotein Ciii (ug/ml) | 0.0341 | Gender | 0.02426 |
Apolipoprotein Ai (mg/ml) | 0.0333 | Testosterone (ng/ml) | 0.002845 |
MRI Eigen Vector #5 | 0.0324 |
lists in order of decreasing coefficient size the features in order of the diminishing of their importance. Among the top 7 most important features are the composite executive function (EF) score and composite memory (Mem), an MRI eigenvector, 3 plasma biomarkers and a demographic. EV#4 includes: L. accumbens vol, R. ventral dorsal column vol, L. & R. amygdala vol, L. & R. hippocampal vol, R. entorhinal vol.