Table 5. Multiple logistic regression analysis including five important predictors (age at diagnosis, disease duration, smoking status, ileal involvement and homozygosity for the p.Leu1007fsX1008 NOD2 mutation (rs2066847)) on the presence of stenoses.

Variable	p-value	OR (95% CI)
Age at diagnosis (per 10 years)	0.447	1.084 [0.881–1.334]
Disease duration (per 10 years)	<0.001	1.934 [1.456–2.570]
Smoking status (any smoking versus non-smoking)	0.007	1.968 [1.207–3.208]
Disease localization (any ileal involvement vs. none)	0.027	2.122 [1.090–4.130]
Homozygosity for the NOD2 p.Leu1007fsX1008 mutation (yes vs. no)	0.009	69.533 [2.945–1641.48]

Smoking is represented by a single contrast; the outcome variable is "stenosis" (n = 639). Significant p-values are shown in bold numbers.