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. 2020 Jul 27;128(7):077009. doi: 10.1289/EHP6047

Table 2.

Descriptive statistics of creatinine-adjusted phthalate and bisphenol concentrations in urine samples measured in pregnancy.

Variables n Min P25 P50 P75 Max
Phthalate metabolite concentrations (μg/g creatinine)a
 LMWP metabolites (weeks of gestation)
  <18 1,274 0.4 109.5 239.5 603.3 102,789.2
  18–25 1,270 4.3 46.8 102.6 238.0 36,050.2
  >25 1,269 21.1 103.0 232.3 530.5 8,131.3
 HMWP metabolites (weeks of gestation)
  <18 1,274 0.6 39.6 68.5 126.6 2,837.4
  18–25b 1,270 2.3 19.3 33.1 59.0 15,577.1
  >25b 1,269 3.6 35.0 52.3 81.9 1,683.6
 DEHP metabolites (weeks of gestation)
  <18 1,274 0.3 31.4 55.2 103.0 2,821.2
  18–25 1,270 1.8 14.4 25.0 46.3 15,574.4
  >25 1,269 3.2 29.6 45.0 71.0 1,673.5
 DNOP metabolites (weeks of gestation)
  <18 1,274 0 0.9 1.6 2.8 106.5
  18–25 1,270 0 0.4 0.8 1.4 65.8
  >25 1,269 0 1.2 1.9 3.0 72.0
 PA (weeks of gestation)
  <18 1,274 0.6 33.8 63.8 123.4 12,433.4
  18–25 1,270 4.3 56.5 111.6 250.1 2,885.2
  >25 1,269 2.6 44.2 73.9 127.1 1,562.4
Total bisphenol concentrations [weeks of gestation (μg/g creatinine)]
<18c 1,274 0.1 1.0 2.1 5.2 982.8
 18–25d 1,270 0 0.6 1.2 2.5 277.6
>25e 1,269 0.1 1.1 2.0 4.2 145.4

Note: Concentrations below the LOD were imputed with LOD divided by the square root of 2. DEHP, di-2-ethylhexylphthalate metabolite; DNOP, di-n-octylphthalate metabolite; HMWP, high-molecular weight phthalate metabolite; LMWP, low-molecular weight phthalate metabolite; LOD, limit of detection; max, maximum; min, minimum; P, percentile; PA, phthalic acid.

a

Phthalate metabolites are grouped into the following categories: LMWP metabolites (sum of mono-methyl phthalate, mono-ethyl phthalate, mono-isobutyl phthalate, and mono-n-butyl phthalate); HMWP metabolites [sum of mono-(2-ethyl-5-carboxypentyl) phthalate, mono-(2-ethyl-5-hydroxyhexyl) phthalate, mono-(2-ethyl-5-oxohexyl) phthalate, mono-[(2-carboxymethyl)hexyl] phthalate, mono(3-carboxypropyl) phthalate, monobenzyl phthalate, mono-hexyl phthalate, and mono-2-heptyl phthalate; DEHP metabolites: [sum of mono (2-ethyl-5 carboxypentyl)phthalate, mono (2-ethyl-5 hydroxyhexyl)phthalate, mono-(2-ethyl-5-oxohexyl)phthalate, and mono-[(2-carboxymethyl)hexyl]phthalate]; DNOP metabolites [mono(3-carboxypropyl) phthalate]; and PA (a proxy for total phthalate exposure).

b

With the exclusion of mono-hexyl phthalate, and mono-2-heptyl phthalate metabolite concentrations.

c

Total bisphenol: sum of bisphenol A, bisphenol F, and bisphenol S.

d

Total bisphenol: sum of bisphenol A and bisphenol S.

e

Total bisphenol: sum of bisphenol A and bisphenol F.