Figure 3.

Ferrichrome induces apoptosis in pancreatic cancer cells. (A) Western blotting revealing that cleaved PARP was significantly increased after 48 h of 10 µg/ml ferrichrome treatment. (B) TUNEL staining indicated the that 1 µg/ml ferrichrome induced apoptosis more strongly than 3 µg/ml 5-FU. Data are presented as the mean ± SD of three independent experiments or fields. Data were analyzed via Williams test or one-way ANOVA followed by Bonferroni's post hoc test. ^*P<0.05 vs. 0 µg/ml or as indicated. PARP, poly (ADP-ribose) polymerase; 5-FU, 5-fluorouracil; DIC, digital image correlation; ns, not significant.