Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic diagram of the ATF3/JunB pathway in endometrial carcinoma, as a representative regulating model of AP-1 binding by to ATF3/ JunB complex. ATF3/JunB complex binds to the AP-1 site of the promoter of JunB to inhibit the expression of JunB, which mitigates cell proliferation, migration and invasion and facilitates cell apoptosis. X indicates transcriptional inhibition. ATF3, activating transcriptional factor 3; AP-1, activator protein 1; ORF, open reading frame.
