Table 1:
Characteristics of All Biopsied Calcifications Included in Study
| Characteristic | All Calcifications (n = 222) | Benign Calcifications (n = 148) | DCIS Calcifications (n = 74) | P Value |
|---|---|---|---|---|
| Patient age at diagnosis (y)*,† | 62(32–84) [51–71] | 61 (32–84) [51–71] | 62 (34–82) [51–71] | … |
| Long axis at diagnosis (mm)‡ | 7 (4–14) | 6 (4–10) | 10 (5–22) | <.001 |
| Race† | … | |||
| White | 135 (60.8) | 90 (60.8) | 45 (60.8) | |
| Black | 87 (39.2) | 58 (39.2) | 29 (39.2) | |
| Pathology at diagnosis | … | |||
| DCIS | 74 (33.3) | 74 (100) | ||
| Fat necrosis | 2 (0.9) | 2 (1.4) | — | |
| Fibroadenoma | 53 (23.9) | 53 (35.8) | — | |
| Fibrocystic changes | 82 (36.9) | 82 (55.4) | — | |
| Fibrosis/scar | 10 (4.5) | 10 (6.8) | — | |
| Papilloma | 1 (0.5) | 1 (0.7) | — | |
| Nuclear grade | … | … | ||
| Low | … | … | 6(8.1) | |
| Intermediate | … | … | 43 (58.1) | |
| High | … | … | 25 (33.8) | |
| Estrogen receptor status | … | |||
| Negative | … | … | 13 (17.6) | |
| Positive | … | … | 61 (82.4) | |
| Progesterone receptor status | … | |||
| Negative | … | … | 15 (20.3) | |
| Positive | … | … | 59 (79.7) | |
| Breast density | .29 | |||
| Fatty | 11(5) | 8 (5.4) | 3(4.1) | |
| Scattered fibroglandular | 85 (38.3) | 61 (41.2) | 24 (32.4) | |
| Heterogeneously dense | 110(49.5) | 67 (45.3) | 43 (58.1) | |
| Extremely dense | 16 (7.2) | 12(8.1) | 4 (5.4) | |
| No. of mammograms included in analysis§ | .75 | |||
| 2 | 49(22.1) | 31 (20.9) | 18 (24.3) | |
| 3 | 92 (41.4) | 61 (41.2) | 31 (41.9) | |
| 4 | 56 (25.2) | 39 (26.4) | 17 (23) | |
| 5 | 17 (7.7) | 10 (6.8) | 7 (9.5) | |
| 6 | 7 (3.2) | 6(4.1) | 1 (1.4) | |
| 7 | 1 (0.5) | 1 (0.7) | 0(0) |
Note.—Unless otherwise stated, data are number of calcifications. Data in parentheses are percentages. DCIS = ductal carcinoma in situ.
*
Data are medians. Data in parentheses are ranges. Data in brackets are interquartile ranges (IQRs).
†
Variable used in matching.
‡
Data are medians. Data in parentheses are IQRs.
§
Includes the mammogram in which the calcifications were first identified prior to a biopsy recommendation.