Table 1:
Properties of the synthesized particles: Number weighted, Z-average sizes, relative fluorescence brightness of ultrabright mesoporous silica nanoparticles in both MESF units (relative to one free dye molecule) and M−1 cm−1, number of dye molecules per particle, quantum yield of the dye molecules after encapsulation (QY), poly-dispersity index (PDI), the zeta potential of nanoparticles, and the number of folate groups per particle.
| Particle type | Number weighted average (nm) | Z-average (nm) | Relative Brightness MESF units | QY | Relative Brightness (M−1 cm−1) | Number of dye molecules per particle | Zeta potential (mV) | PDI | No. of FA per particle |
|---|---|---|---|---|---|---|---|---|---|
| SiSB | 33 ± 2 | 53 ± 0.2 | 740 ± 40 | 0.79 | (470 ± 10) x105 | 790 ± 20 | +42 ± 4 | 0.14 | N/A |
| SiSB-PEG | 34 ± 1 | 64 ± 0.3 | 690 ± 20 | 0.57 | (450 ± 10)x 105 | 990 ± 30 | +40 ± 2 | 0.17 | N/A |
| SiSB-PEGFA-PEG | 31 ± 2 | 58 ± 0.4 | 360 ± 30 | 0.15 | (230 ± 30) x 105 | 1910 ±190 | +33 ± 3 | 0.24 | 820 ± 80 |
| SiSB-PFFA | 40 ± 1 | 69 ± 0.6 | 350 ± 20 | 0.16 | (230 ± 10) x 105 | 1770 ±100 | +17 ± 1 | 0.21 | 4100 ± 210 |
| SiSB-PEGFA-PFFA | 38 ± 2 | 67 ± 0.6 | 214 ± 17 | 0.1 | (140 ± 7) x 105 | 1720 ±150 | +19 ± 1 | 0.21 | 4400 ± 420 |