Table II.

Direct context specific association between gene expression and DNA methylation¹

3′ Regulatory Region	Methylation Difference	Expression Fold Change
ADA	25.58	2.29
FAN46A	−29.05	−2.49
TCF7L1	−23.81	4.58
ZFP36L1	26.74	−1.79
5′ Regulatory Region	Methylation Difference	Expression Fold Change
ANKRD22	−29.07	5.17
APMAP	−25.09	−2.09
CECR2	−21.25	−2.67
FAM65B	25.26	1.76
MIR3945HG	−27.06	3.57
PDCD1LG2	−35.49	3.05
TMEM177	21.52	3.79
UBASH3B	−25.14	−1.75
ZNF385A	−25.55	−2.32
Introns	Methylation Difference	Expression Fold Change
BHLHE40-AS1	−22.77	7.74
CD180	−26.39	−2.86
FOXN3	−24.01	−1.63
GPR157	−28.74	−2.53
KIAA0930	−21.57	−2.30
KIAA0930	−21.93	−2.30
LINC00862	−30.47	7.95
LY86	21.61	−3.37
MAFA	22.25	3.05
MEGF6	−25.46	3.05
MEIKIN	24.45	−3.47
RAPGRP1	24.46	2.17
RGS2	−21.81	−2.92
RPS6KA2	−26.85	−2.91
SH3PXD2B	−29.64	2.34
SLC25A37	−24.23	2.33
SORT1	−24.42	−2.43
TBC1D1	−22.87	2.80
TIMM13	−31.52	−2.15
Exons	Methylation Difference	Expression Fold Change
AKR1A1	−23.10	−2.10
CMYA5	24.93	4.85
FAM46A	−29.05	−2.49
FAM78A	−30.60	−1.89
GBP5	−23.07	2.56
KLF2	23.66	2.87
LGALS12	−21.56	−4.23
SNORD17	−22.49	2.977
TCF7L1	−23.81	4.58
ZFP36L1	26.74	−1.79
ZFP36L1	23.12	−1.79

¹Summary of direct context specific changes in genes with statistically significant expression and methylation changes. Gene names in column have been categorized by specific contexts in which methylation changes were observed. Columns two and three represent changes in methylation and gene expression respectively.