Table 4. Baseline characteristics of patients at initial diagnosis of HCC in the three groups.
| Characteristics | 2000–2003 | 2004–2008 | 2009–2012 | P value | |
|---|---|---|---|---|---|
| No. | 1,097 | 1,425 | 1,494 | ||
| Age, yr | 62.8 ± 11.9 | 60.8 ± 11.2 | 60.3 ± 10.3 | < 0.001 | |
| < 40 | 34 (3.1) | 32 (2.2) | 22 (1.2) | ||
| 41–50 | 123 (11.2) | 202 (14.2) | 204 (13.7) | ||
| 51–60 | 258 (23.5) | 443 (31.1) | 515 (34.5) | ||
| 61–70 | 336 (30.6) | 403 (28.3) | 430 (28.8) | ||
| > 70 | 346 (31.5) | 344 (24.2) | 323 (21.6) | ||
| Sex, male | 810 (73.8) | 1,087 (76.3) | 1,164 (77.9) | 0.017 | |
| Etiology | < 0.001 | ||||
| HBV | 750 (68.4) | 895 (62.8) | 900 (60.2) | ||
| HCV | 88 (8.0) | 134 (9.4) | 163 (10.9) | ||
| Alcohol | 194 (17.7) | 276 (19.4) | 314 (21.0) | ||
| NAFLD | 14 (1.3) | 39 (2.7) | 45 (3.0) | ||
| HBV+HCV | 35 (3.2) | 29 (2.0) | 12 (0.8) | ||
| Other | 16 (1.5) | 52 (3.6) | 60 (4.0) | ||
| CTP class | < 0.001 | ||||
| CTP A | 281 (27.2) | 418 (35.1) | 463 (50.7) | ||
| CTP B | 666 (64.5) | 664 (55.8) | 365 (40.0) | ||
| CTP C | 85 (8.2) | 109 (9.2) | 85 (9.3) | ||
| Image study | < 0.001 | ||||
| CT | 624 (56.9) | 928 (65.1) | 1,078 (72.2) | ||
| USG | 474 (43.2) | 328 (23.0) | 202 (13.5) | ||
| MRI | 22 (2.0) | 72 (5.1) | 214 (14.3) | ||
Data are presented as mean ± standard deviation or number (%).
HCC = hepatocellular carcinoma, HBV = hepatitis B virus, HCV = hepatitis C virus, NAFLD = non-alcoholic fatty liver disease, CTP = Child-Turcotte-Pugh, CT = computed tomography, USG = ultrasonography, MRI = magnetic resonance imaging.