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. 2020 Apr 13;37(3):149–158. doi: 10.12701/yujm.2020.00157

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Copyright © 2020 Yeungnam University College of Medicine

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 3. — (A, B) Kellgren-Lawrence grade III osteoarthritis is observed in the left knee anteroposterior and 45° flexion standing radiographs in a 49-year-old woman. (C) The scanography image shows neutral alignment of the both lower extremities. (D, E) Coronal T2-weighted fat suppressed magnetic resonance image (MRI) and arthroscopy show the focal chondral defects of International Cartilage Repair Society (ICRS) grade IV in the lateral femoral condyle and lateral tibial plateau. (F) Surgical implantation is performed using a commercialized mixture of human umbilical cord blood-derived mesenchymal stem cells and hyaluronic acid gel (Cartistem). (G, H) The coronal T2-weighted fat suppressed MRI and second-look arthroscopy confirm regenerated cartilage at 18 months after surgery.