Table II:
Age adjusted mean cognitive test scores and percent of patients impaired on each cognitive test.
| Test | N | Direction Of Better Score | Age Adjusted Scorea (mean (SD)) | % Impairedb |
|---|---|---|---|---|
| NIH-TB Total Composite Score (global cognition) | 150 | Higher | 106.81 (14.13) | 8.7 |
| Dimensional Change Card Sort (executive function) | 150 | Higher | 108.81 (15.84) | 3.3 |
| Oral Reading Recognition Test (reading decoding) | 150 | Higher | 110.35 (17.37) | 8.0 |
| Picture Vocabulary Test (vocabulary comprehension) | 150 | Higher | 108.43 (12.56) | 3.3 |
| Flanker Inhibitory Control & Attention (attention & executive function) | 150 | Higher | 93.59 (10.67) | 20.7 |
| List Sorting Working Memory (memory) | 150 | Higher | 104.74 (13.78) | 8.0 |
| Pattern Comparison (processing speed) | 150 | Higher | 98.65 (17.74) | 23.3 |
| Picture Sequence Matching (memory) | 150 | Higher | 100.82 (14.85) | 12.0 |
| COWA (verbal fluency) | 148e | Higher | 42.61 (10.49)f | 13.3 |
| HVLT-R Total Correct Immediate Recall (memory) | 150 | Higher | 46.19 (11.68) | 28.0 |
| HVLT-R Total Correct Delayed Recall (memory) | 150 | Higher | 43.91 (12.34) | 36.7 |
| TMT-A (attention) | 148e | Lower | 51.70 (8.89) | 7.3 |
| TMT-B (executive function) | 148e | Lower | 51.22 (9.96) | 11.3 |
| FACT-Cog Perceived Cognitive Impairment Subscale (self-report) | 149c | Higher | 58.21 (11.68) | N/Ad |
NIH-TB: National Institutes of Health Toolbox Cognition Battery; FACT-Cog: Functional Assessment After Cancer Treatment Cognition; COWA: Controlled Word Association Test; HVLT-R: Hopkins Verbal Learning Test Revised; TMT-A/B: Trail Making Test A or B.
a
NIH Toolbox outcomes are age adjusted scaled scores (μ=100), paper tests are age adjusted T-scores (μ=50),
b
impairment defined as an age-adjusted score >1 SD below the normative mean,
c
one participant did not return study questionnaires,
d
normative mean unavailable,
e
two participants did not complete these tests due to time constraints,
f
mean COWA score adjusted for age and education