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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Ophthalmology. 2020 Feb 25;127(8):1000–1011. doi: 10.1016/j.ophtha.2020.02.022

Table 1.

Baseline Demographics and Clinical Characteristics among Medicare Beneficiaries based on Dementia Status, 2009–20151,2 (N=4,451,200)

Prevalent Dementia3
N(%)
Incident Dementia3
N(%)
Any Dementia N (%) No Dementia N(%) p-value4
Number of beneficiaries 275717 (6.2) 63954 (1.4) 339671 (7.6) 4111529 (92.4) <0.0001
Age at enrollment (years)
 65–74 73111 (26.5) 23307 (36.4) 96418 (28.4) 2532630 (61.6) <0.0001
 75–84 136102 (49.4) 30494 (47.7) 166596 (49.0) 1288545 (31.3)
 85–94 63049 (22.9) 9858 (15.4) 72907 (21.5) 276800 (6.7)
 Over 95 3455 (1.3) 295 (0.5) 3750 (1.10) 13554 (0.3)
Gender <0.0001
 Female 190536 (69.1) 41495 (64.9) 232031 (68.3) 2373125 (57.7)
 Male 85181 (30.9) 22459 (35.1) 107640 (31.7) 1738404 (42.3)
Race / ethnicity <0.0001
 White 230288 (83.5) 53840 (84.2) 284128 (83.6) 3570491 (86.8)
 Black 28433 (10.3) 6380 (10.0) 34813 (10.2) 294340 (7.2)
 Hispanic 7735 (2.8) 1514 (2.4) 9249 (2.72) 72724 (1.8)
 Asian 5285 (1.9) 1277 (2.0) 6562 (1.93) 89647 (2.2)
 Native American, Other, or Unknown 3976 (1.4) 943 (1.5) 4919 (1.45) 84327 (2.1)
Geographic Location5 <0.0001
 Rural 58017 (21.0) 14234 (22.3) 72251 (21.3) 1068645 (26.0)
 Urban 217700 (79.0) 49720 (77.7) 267420 (78.7) 3042884 (74.0)
Year of Study Period Entry <0.0001
 2009 242565 (88.0) 59712 (93.4) 302277 (89.0) 3478438 (84.6)
 2010 5804 (2.1) 1113 (1.7) 6917 (2.04) 94767 (2.3)
 2011 6628 (2.4) 1068 (1.7) 7696 (2.27) 107498 (2.6)
 2012 5937 (2.2) 743 (1.2) 6680 (1.97) 104428 (2.5)
 2013 7700 (2.8) 838 (1.3) 8538 (2.51) 163635 (4.0)
 2014 5670 (2.1) 425 (0.7) 6095 (1.79) 124845 (3.0)
 2015 1413 (0.5) 55 (0.1) 1468 (0.43) 37918 (0.9)
Baseline Eye Care Status6 <0.0001
 No Eye Care Visit 79983 (29.0) 22721 (35.5) 102704 (30.2) 1151138 (28.0)
 Optometrist Only 50981 (18.5) 9873 (15.4) 60854 (17.9) 665191 (16.2)
 Ophthalmologist Only 99594 (36.1) 23281 (36.4) 122875 (36.2) 1733153 (42.2)
 Both Optometrist and Ophthalmologist 45159 (16.4) 8079 (12.6) 53238 (15.7) 562047 (13.7)
Baseline Cataract Surgery7 <0.0001
 Prior cataract surgery 31332 (11.4) 7174 (11.2) 38506 (11.3) 549929 (13.4)
 No evidence of prior cataract surgery 244385 (88.6) 56780 (88.8) 301165 (88.7) 3561600 (86.6)
Other Clinical Comorbidities
 Cataract diagnosis 99225 (36.0) 21050 (32.9) 120275 (35.4) 1658636 (40.3) <0.0001
 Diabetic Retinopathy diagnosis 8936 (3.2) 1717 (2.7) 10653 (3.14) 125050 (3.0) <0.0001
 Age-related Macular Degeneration diagnosis 43911 (15.9) 7637 (11.9) 51548 (15.2) 476757 (11.6) <0.0001
 Glaucoma diagnosis 52613 (19.1) 8525 (13.3) 61138 (18.0) 747167 (18.2) <0.0001
 Depression diagnosis 39692 (14.4) 4731 (7.4) 44423 (13.1) 112904 (2.7) <0.0001
Charlson Comorbidity Index8 <0.0001
 2–3 29406 (10.7) 13340 (20.9) 42746 (12.6) 1582514 (38.5)
 4–5 99561 (36.1) 25416 (39.7) 124977 (36.8) 1411249 (34.3)
 6–7 81746 (29.6) 15236 (23.8) 96982 (28.6) 702426 (17.1)
 8+ 65004 (23.6) 9962 (15.6) 74966 (22.1) 415340 (10.1)
Skill Nursing stay 11702 (4.2) 978 (1.5) 12680 (3.73) 30144 (0.7) <0.0001
1

2006–2009 data were used to define the lookback period and establish baseline beneficiary characteristics; 2015 data was only applicable for regression analysis since beneficiaries were required to have at least one year of enrollment after the end of the “lookback period.”

2

Results presented with column percentages for all variables except number of beneficiaries (row percentage)

3

Prevalent dementia was recorded during the initial 3-year lookback period; incident dementia was a dementia diagnosis that was first recorded during the subsequent follow-up period and prior to first eye care visit during the followup period

4

Chi-square test statistic

5

Based on rural urban commuting area codes, in which rural areas represent small urban clusters with a population of 49,000 or fewer persons.

6

Based on receipt of eye care services during beneficiaries’ “lookback period” (first three years of observed plan enrollment)

7

Beneficiaries who had evidence of baseline/prior cataract surgery during their initial 3-year lookback period were excluded from the study sample used to identify likelihood of cataract surgery in the subsequent followup period.

8

We omitted the dementia variable from computation of Charlson Index, such that the lowest permitted Charlson Index score was 2.