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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Leuk Lymphoma. 2020 Apr 8;61(7):1669–1677. doi: 10.1080/10428194.2020.1742900

Figure 2.

Figure 2.

Association of rs2231137 on ABCG2 gene with pharmacokinetics data. Each of the four pharmacokinetics metrics (Cmaxtotal, Cmaxfree, AUCtotal, and AUCfree) in plasma following teriflunomide treatment was plotted against the genotype of a mutation (rs2231137) in ABCG2. Each dot represents one patient, with the red error bar representing mean plus and minus the standard deviation. One-way ANOVA test was applied for each PK metric (nominal P = 0.00092 for AUCfree; P = 0.2138 for Cmaxtotal, P = 0.0746 for Cmaxfree, and P = 0.8502 for AUCtotal).