. Author manuscript; available in PMC: 2021 Aug 1.

Published in final edited form as: Ophthalmology. 2020 Feb 7;127(8):1105–1112. doi: 10.1016/j.ophtha.2020.01.052

Table 1. Clinical and demographic features of study cohort displayed by peak disease severity.

Features of infants who developed treatment-requiring (TR) with aggressive posterior retinopathy of prematurity (AP-ROP) are significantly different compared to infants who developed other disease categories.

Peak severity	n (eyes)	Mean birth weight, g (SD)	Mean gestational age, wk (SD)	Mean PMA at peak, wk (SD)
No ROP	841	1142 (309)^***	28.8 (2.0)^***	Not applicable
Mild ROP	584	921 (264)^***	27.0 (2.0)^***	37.0 (3.8)^***
Type 2 ROP or pre-plus	282	742 (210)^*	25.7 (1.8)^***	38.2 (4.4)^***
TR without AP-ROP	120	679 (179)^**	25.0 (1.5)^**	36.9 (2.8)^***
TR with AP-ROP	62	617 (119)	24.3 (0.9)	34.7 (1.3)

Statistically significant difference compared to TR with AP-ROP, p<0.05

^**

Statistically significant difference compared to TR with AP-ROP, p<0.01

^***

Statistically significant difference compared to TR with AP-ROP, p<0.001

g = grams; wk = weeks; SD = standard deviation; PMA = post-menstrual age; ROP = retinopathy of prematurity; TR = treatment-requiring; AP-ROP = aggressive posterior retinopathy of prematurity