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. Author manuscript; available in PMC: 2021 Sep 1.

Published in final edited form as: J Surg Res. 2020 Apr 30;253:173–184. doi: 10.1016/j.jss.2020.03.051

Table 2.

Chymase activity in left and right atria

	Total			Male			Female
	n	Mean ± SEM	P value	n	Mean ± SEM	P value	n	Mean ± SEM	P value
LA chymase activity
CHF	3	84.3±5.7	0.054	3	84.3±5.7	0.018	0		N/A
Non-CHF	27	51.0±5.4	0.054	16	46.1±6.1	0.018	11	58.0±9.9	N/A

MR	18	58.5±6.8	0.328	10	49.4±8.1	0.645	8	70.0±10.5	0.039
Non-MR	12	47.9±8.3	0.328	9	55.2±9.7	0.645	3	25.9±7.8	0.039

ARB	8	39.4±8.6	0.085	6	34.9±5.5	0.052	2	52.7±36.8	0.82
Non-ARB	22	59.7±6.1	0.085	13	60.1±7.7	0.052	9	59.2±10.6	0.82

RA chymase activity
HT	61	48.6±5.0	0.052	48	46.7±5.5	0.023	13	55.3±12.4	0.74
Non-HT	37	34.3±4.3	0.052	27	28.6±3.7	0.023	10	49.4±11.6	0.74

MVD	5	70.0±25.3	0.080	1	59.09±	N/A	4	72.8±32.5	0.290
Non-MVD	92	41.5±3.5	0.080	73	39.63±3.94	N/A	19	48.6±7.9	0.290

CHF: congestive heart failure; MR: mitral regurgitation; ARB: Angiotensin II receptor blocker; HT: hypertension; MVD: mitral valve disease.