. Author manuscript; available in PMC: 2021 Sep 1.

Published in final edited form as: J Surg Res. 2020 Apr 30;253:173–184. doi: 10.1016/j.jss.2020.03.051

Table 3.

Chymase mRNA levels in left and right atria

	Total			Male			Female
	n	Mean ± SEM	P value	n	Mean ± SEM	P value	n	Mean ± SEM	P value
LA chymase mRNA
Stroke	3	2.44±0.86	0.0092	1	1.08	N/A	2	3.12±0.92	0.0017
Non-Stroke	27	1.26±0.11	0.0092	18	1.37±0.15	N/A	9	1.05±0.15	0.0017

PO-AF	14	1.76±0.25	0.009	10	1.64±0.23	0.028	4	2.05±0.73	0.125
Non-PO-AF	16	1.05±0.09	0.009	9	1.04±0.08	0.028	7	1.06±0.18	0.125

MVD	5	1.91±0.58	0.0779	1	0.99	N/A	4	2.14±0.69	0.076
Non-MVD	23	1.23±0.12	0.0779	16	1.33±0.15	N/A	7	1.02±0.19	0.076

ARB	8	1.06±0.23	0.1729	6	1.16±0.26	0.3570	2	0.77±0.52	0.337
Non-ARB	22	1.50±0.17	0.1729	13	1.45±0.17	0.3570	9	1.57±0.35	0.337

RA chymase mRNA
HT	52	1.34±0.25	0.1886	41	1.26±0.29	0.4989	11	1.62±0.50	0.075
Non-HT	34	0.85±0.25	0.1886	26	0.96±0.32	0.4989	8	0.50±0.08	0.075

CAD	52	0.93±0.15	0.0698	43	0.87±0.15	0.0381	9	1.20±0.50	0.990
Non-CAD	24	1.71±0.54	0.0698	15	2.01±0.82	0.0381	9	1.19±0.44	0.990

MVD	4	2.45±1.22	0.1127	0		N/A	4	2.45±1.22	0.026
Non-MVD	81	1.09±0.18	0.1127	66	1.16±0.22	N/A	15	0.80±0.18	0.026

AVD	25	1.72±0.49	0.0389	21	1.75±0.57	0.0638	4	1.59±0.93	0.419
Non-AVD	59	0.90±0.15	0.0389	45	0.89±0.17	0.0638	14	0.94±0.33	0.419

BB	50	0.95±0.13	0.1659	39	0.86±0.13	0.1020	11	1.23±0.42	0.752
Non-BB	35	1.46±0.39	0.1659	27	1.58±0.49	0.1020	8	1.02±0.48	0.752

PO-AF: postoperative atrial fibrillation; ARB: Angiotensin II receptor blocker; HT: hypertension; CAD: coronary artery disease; MVD: mitral valve disease; AVD: aortic valve disease; BB: Beta blocker.