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. Author manuscript; available in PMC: 2020 Jul 28.
Published in final edited form as: Cold Spring Harb Symp Quant Biol. 2020 Jun 3;84:11–20. doi: 10.1101/sqb.2019.84.040402

Figure 1.

Figure 1.

Eukaryotic mRNA is processed concurrently with transcription to modify the transcript output. Processing can include 5′-end capping with 7-methylguanosine, splicing, and polyadenylation cleavage. The rate of elongation is also non-uniform along the gene body.