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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Ophthalmology. 2020 Feb 25;127(8):1097–1104. doi: 10.1016/j.ophtha.2020.02.024

Table 1.

Residual natural vision, anatomical and functional outcomes with the implant.

Test \ Patient 1 2 3 4 5
Residual peripheral vision
Pre-op eccentric natural acuity in the study eye 20/400 LogMAR 1.3 20/800 LogMAR 1.6 20/1000 LogMAR 1.7 20/500 LogMAR 1.4 20/500 LogMAR 1.4
Post-op eccentric natural acuity in the study eye (12 months) 20/320 LogMAR 1.2 20/800 LogMAR 1.6 20/800 LogMAR 1.6 20/400 LogMAR 1.3 20/400 LogMAR 1.3
Implant location
Implant location in the macula Intra-choroidal Central subretinal Central subretinal Off-center subretinal Central subretinal
Average distance from implant to bottom of INL at 3, 6, 12 months (μm) 127 34 43 37 51
103 28 35 38 39
138 39 39 35 37
Perceptual stimulation thresholds
Chronaxie (ms) NA 2.5 2.3 2.2 2.1
Rheobase (mW/mm2) NA 1.0 0.4 1.4 0.5
Threshold pulse duration (ms) for 3mW/mm2 2.1 0.8 0.7 1.0 0.8
Central vision
Natural central visual perception None None None None None
Prosthetic bar orientation, % correct, [95% CI], % 28 [20–40] 96 [93–98] 96 [93–98] 94 [86–98] 88 [75–95]
Prosthetic min. bar width on retina, pix, (% correct) [95% CI], % 2 (90%) [55–100] 1 (100%) [69–100] 1 (70%) [35–93] 1 (50%) [19–82] 1 (80%) [44–97]
Prosthetic central acuity Min. Landolt C gap, pix Light perception 20/550 LogMAR 1.44 1.3 pix 20/500 LogMAR 1.4 1.2 pix 20/800 LogMAR 1.6 1.9 pix 20/460 LogMAR 1.37 1.1 pix