Table 3.
Clinical–pathologic characteristics of cases classified as “send” compared with cases labeled as “do not send-expect low”.
| Labeled “send”; n = 658 | Labeled “do not send-expect low”; n = 1518 | p value | |
|---|---|---|---|
| Age, mean | 58 years | 59 years | 0.1664 |
| Tumor size, mean | 2.2 cm | 1.8 cm | <0.0001 |
| Nottingham Grade | |||
| Grade I | 11 (2%) | 492 (32.5%) | <0.0001 |
| Grade II | 329 (50%) | 1022 (67%) | |
| Grade III | 318 (48%) | 4 (0.5%) | |
| PR status | |||
| Negative | 81 (12%) | 88 (6%) | <0.0001 |
| Positive | 577 (88%) | 1430 (94%) | |
| PR H-score mean | 129 | 173 | <0.0001 |
| ER H-score mean | 241 | 262 | <0.0001 |
| Ki-67 index mean | 35% | 14% | <0.0001 |
| Nodal status | |||
| Negative | 550 (84%) | 1312 (86%) | 0.1207 |
| Positive | 94 (14%) | 180 (12%) | |
| ITC | 4 (0.5%) | 6 (0.5%) | |
| Unknown | 10 (1.5%) | 20 (1.5%) | |
| Histologic type | |||
| Ductal, NST | 338 (51%) | 715 (47%) | <0.0001 |
| Lobular, classic | 27 (4%) | 140 (9%) | |
| Other | 27 (4%) | 54 (4%) | |
| Not recorded | 266 (40%) | 609 (40%) | |
ER estrogen receptor, PR progesterone receptor, ITC isolated tumor cell, NST no special type.